As described above, inhibition of IL-6 trans-signaling has been shown to mitigate inflammation responses (Risby-Jones et al., 2025), and targeting miRNAs has a potential to modulate glial cell functions (Hoye et al., 2018
Macroangiopathy includes AS of large and medium arteries (aorta, coronary, renal, basilar, and peripheral arteries), whereas microangiopathy includes endothelial damage to vessels between primary arterioles and venules, vascular basement membrane thickening, microthrombosis, platelet and red blood cell adhesion aggregation, and microcirculatory disorders
What leads to glutathione deficiency
It helps neutralize reactive oxygen species (ROS) and supports mitochondrial health, making it vital for energy production and cellular defense, especially during physical activity